Description

(S)-1-Amino-3-(3,4-Dihydroisoquinolin-2(1H)-Yl)Propan-2-Ol is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, which is critical for biological activity. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), especially in the areas of neurology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to introduce stereogenic centers into complex molecular architectures.
• Ligand and Catalyst Development: Acts as a precursor for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Peptidomimetics: Utilized in the design and synthesis of peptide-like molecules that mimic the structure and function of natural peptides.
• Chemical Biology Probes: Incorporated into molecules designed to study biological processes and identify new drug targets.

Basic Information

Item	Details
Product Name	(S)-1-Amino-3-(3,4-Dihydroisoquinolin-2(1H)-Yl)Propan-2-Ol
CAS No.	1616077-51-0
Molecular Formula	C₁₂H₁₈N₂O
Molecular Weight	206.28 g/mol
Synonyms	(S)-2-Amino-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-3-ol; (S)-1-Amino-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-2-ol; (S)-1-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-2-aminopropan-3-ol; (S)-2-Amino-1-(3,4-dihydro-1H-isoquinolin-2-yl)propan-3-ol; (S)-1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-aminopropan-2-ol; (S)-Amino-THIQ-Propanol derivative; Chiral THIQ-amino alcohol
EINECS	Contact for details

Quality Control

Our production of (S)-1-Amino-3-(3,4-Dihydroisoquinolin-2(1H)-Yl)Propan-2-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials undergo comprehensive analytical testing, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.