Description

[2H6]-Bisphenol A β-D-Glucuronide is a stable isotope-labeled internal standard of the Bisphenol A metabolite, Bisphenol A glucuronide. This high-purity compound is essential for achieving accurate and reliable quantification in advanced analytical methods, particularly liquid chromatography-mass spectrometry (LC-MS/MS). It is a critical reagent for researchers and quality control laboratories in the pharmaceutical, environmental monitoring, and toxicology sectors who require definitive analysis of BPA exposure and metabolism.

Application

• Quantitative Bioanalysis: Serves as an internal standard for the precise LC-MS/MS measurement of Bisphenol A glucuronide in biological matrices such as urine, serum, and plasma.
• Pharmacokinetic & Toxicokinetic Studies: Enables accurate tracking of BPA metabolism, absorption, distribution, and excretion in clinical and preclinical research.
• Human Biomonitoring: Critical for large-scale population studies assessing environmental exposure to Bisphenol A, supporting public health research.
• Method Development & Validation: Used to establish and validate robust analytical protocols in compliance with guidelines like FDA 21 CFR Part 11.
• Quality Control & Assurance: Ensures accuracy and compensates for matrix effects in high-throughput testing laboratories.
• Reference Standard: Acts as a certified reference material for calibrating instruments and verifying analytical results.

Basic Information

Item	Details
Product Name	[2H6]-Bisphenol A β-D-Glucuronide
CAS No.	1610029-53-2
Molecular Formula	C21H20D6O8
Molecular Weight	~416.42 g/mol
Synonyms	Bisphenol A-d6 Glucuronide; Deuterated BPA Glucuronide; BPA-d6 Glucuronide; 4,4'-(Propane-2,2-diyl)diphenol-d6 glucuronide; BPA-G-d6; [2H6]-BPA-G; Bisphenol A Glucuronide (hexadeuterated); Internal Standard for BPA-G
EINECS	Contact for details

Quality Control

Every batch of [2H6]-Bisphenol A β-D-Glucuronide is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Identity, purity, and isotopic enrichment are verified by advanced techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to ensure traceability and support your regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.