Description

n-Methyl-1-(1,3-thiazol-4-yl)methanamine dihydrochloride is a high-purity, pharmaceutically relevant organic salt. This compound is a critical building block and intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Chemical Research & Development: Serves as a versatile building block for constructing novel molecular libraries in medicinal chemistry and lead optimization programs.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for potential API manufacturing under cGMP conditions.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Bioconjugation & Probe Synthesis: The amine functionality allows for its use in creating labeled compounds or probes for biochemical and pharmacological studies.

Basic Information

Product Name	n-Methyl-1-(1,3-thiazol-4-yl)methanamine Dihydrochloride
CAS No.	1609403-13-5
Molecular Formula	C6H11N2S • 2HCl
Molecular Weight	227.15 g/mol (for dihydrochloride salt)
Synonyms	4-Thiazolemethanamine, N-methyl-, dihydrochloride; (1,3-Thiazol-4-yl)-N-methylmethanamine dihydrochloride; 4-((Methylamino)methyl)thiazole dihydrochloride; N-Methyl-1-(thiazol-4-yl)methanamine dihydrochloride; N-Methyl-4-thiazolemethanamine dihydrochloride; 1609403-13-5; UNII-8I4Z5P8V4T
EINECS	Contact for details

Quality Control

Our n-Methyl-1-(1,3-thiazol-4-yl)methanamine dihydrochloride is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing results from HPLC, NMR, and other relevant tests. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and can be aligned with cGMP standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.