Description

3-[(E)-4-(Furan-2-Yl)-2-Oxobut-3-Enyl]-3-Hydroxy-1H-Indol-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex molecular architecture combining indole and furan moieties. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting specific enzymatic pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those with heterocyclic frameworks.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new active pharmaceutical ingredients (APIs).
• Biochemical Probe Development: Acts as a precursor for creating specialized probes to study biological mechanisms and enzyme inhibition.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing complex, high-value specialty chemicals.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic synthesis and chemical biology.

Basic Information

Product Name	3-[(E)-4-(Furan-2-Yl)-2-Oxobut-3-Enyl]-3-Hydroxy-1H-Indol-2-One
CAS No.	1609385-99-0
Molecular Formula	C16H13NO4
Molecular Weight	283.28 g/mol
Synonyms	3-Hydroxy-3-[(1E)-4-(2-furanyl)-2-oxo-1-buten-1-yl]-1H-indol-2(3H)-one; (3E)-3-[4-(Furan-2-yl)-2-oxobut-3-en-1-yl]-3-hydroxyindolin-2-one; 3-[(E)-4-(2-Furyl)-2-oxobut-3-en-1-yl]-3-hydroxy-1H-indol-2-one; Furan-Indole Derivative; Light-sensitive indole-furan conjugate
EINECS	Contact for details

Quality Control

Our 3-[(E)-4-(Furan-2-Yl)-2-Oxobut-3-Enyl]-3-Hydroxy-1H-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a Certificate of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure it meets the stringent requirements for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.