Description

1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 4-chloro-, 1,1-dimethylethyl ester is a high-purity, advanced pharmaceutical intermediate (API) with the CAS registry number 1609259-26-8. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular architecture. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, particularly in oncology and central nervous system (CNS) research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing fused heterocyclic systems, enabling structure-activity relationship (SAR) studies.
• Research & Development (R&D): Essential for academic and industrial laboratories exploring new chemical entities and novel synthetic pathways.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for candidate drugs during preclinical and clinical development phases.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) producing batches for regulatory submission and clinical trials.

Basic Information

Product Name	1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 4-chloro-, 1,1-dimethylethyl ester
CAS No.	1609259-26-8
Molecular Formula	C13H15ClN2O2
Molecular Weight	266.72 g/mol
Synonyms	4-Chloro-1-(tert-butoxycarbonyl)-1H-pyrrolo[3,2-c]pyridine; tert-Butyl 4-chloro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate; 4-Chloro-1-Boc-1H-pyrrolo[3,2-c]pyridine; 1-Boc-4-chloro-1H-pyrrolo[3,2-c]pyridine; 4-Chloro-1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester; 1609259-26-8; 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 4-chloro-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 4-chloro-, 1,1-dimethylethyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.