Description

(2-Amino-5-Bromo-4-Fluoro-Phenyl)-Methanol is a high-purity, multi-functional aromatic building block featuring amino, bromo, fluoro, and hydroxymethyl substituents. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development, where its unique substitution pattern enables precise structural modifications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to create novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the halogen and amino groups for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced polymers and organic electronic materials due to its aromatic core and functional handles.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	(2-Amino-5-Bromo-4-Fluoro-Phenyl)-Methanol
CAS No.	1603209-47-7
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	2-Amino-5-bromo-4-fluorobenzyl alcohol; (2-Amino-5-bromo-4-fluorophenyl)methanol; 5-Bromo-4-fluoro-2-aminobenzyl alcohol; 2-(Aminomethyl)-4-bromo-5-fluorophenol (tautomer); 4-Bromo-5-fluoroanthranilyl alcohol; Benzenemethanol, 2-amino-5-bromo-4-fluoro-; 1603209-47-7; 2-Amino-4-bromo-5-fluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our (2-Amino-5-Bromo-4-Fluoro-Phenyl)-Methanol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.