Description

(1R,3R)-1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2,2-Dichloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate is a high-purity, complex heterocyclic compound featuring a tetrahydro-β-carboline core, which is a privileged scaffold in medicinal chemistry. This compound is of significant interest for its potential as a key synthetic intermediate or a pharmacologically active scaffold in advanced pharmaceutical research and development. It is primarily targeted at R&D chemists and process development scientists working in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, well-characterized building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its complex, drug-like tetrahydro-β-carboline structure.
• Process Chemistry Development: Employed in the optimization and scale-up of synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe to study specific biological pathways and protein interactions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development of complex molecules for client projects.

Basic Information

Product Name	(1R,3R)-1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2,2-Dichloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate
CAS No.	1598416-08-0
Molecular Formula	C23H18Cl2N2O5
Molecular Weight	473.31 g/mol
Synonyms	(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(2,2-dichloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester; (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2-(2,2-dichloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate; Tetrahydro-β-carboline derivative; Dioxolane-substituted β-carboline; CAS 1598416-08-0
EINECS	Contact for details

Quality Control

Our (1R,3R)-1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2,2-Dichloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D, and we can provide material with specifications aligned with client needs for advanced projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.