Description

3-Fluoro-2-Methoxypyridine-4-Boronic Acid is a high-value boronic acid derivative and a versatile building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a building block for synthesizing specialized ligands used in homogeneous catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient pyridine core.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated and methoxylated pyridine scaffolds.

Basic Information

Product Name	3-Fluoro-2-Methoxypyridine-4-Boronic Acid
CAS No.	1598387-84-8
Molecular Formula	C6H7BFNO3
Molecular Weight	170.94 g/mol
Synonyms	(3-Fluoro-2-methoxypyridin-4-yl)boronic acid; 4-Borono-3-fluoro-2-methoxypyridine; 3-Fluoro-2-methoxy-4-pyridineboronic acid; 2-Methoxy-3-fluoropyridine-4-boronic acid; 1598387-84-8; 3-Fluoro-2-methoxypyridine-4-boronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methoxypyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.