Description

(5-Chloro-1H-Indol-2-Yl)Methanamine Hydrochloride is a high-purity, functionalized indole derivative supplied as a stable hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the development of novel active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science research sectors for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science: A monomer or functional unit for creating advanced polymers and organic electronic materials with specific optoelectronic properties.
• Academic & Contract Research: Essential for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(5-Chloro-1H-Indol-2-Yl)Methanamine Hydrochloride
CAS No.	1588440-91-8
Molecular Formula	C9H10Cl2N2
Molecular Weight	217.10 g/mol
Synonyms	5-Chloro-1H-indole-2-methanamine hydrochloride; 2-(Aminomethyl)-5-chloro-1H-indole hydrochloride; (5-Chloro-1H-indol-2-yl)methanamine HCl; 5-Chloro-2-(aminomethyl)indole hydrochloride; 5-Chloroindole-2-methylamine hydrochloride; 1H-Indole-2-methanamine, 5-chloro-, hydrochloride; 5-Chloro-2-indolylmethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Chloro-1H-Indol-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.