Description

Phenol, 5-Bromo-2-[(2R)-5-Bromo-2,3-Dihydro-1H-Indol-2-Yl]- is a specialized brominated indole derivative, a high-value chiral building block in advanced organic synthesis. This compound matters for its precise stereochemistry and functional groups, which are critical for constructing complex molecular architectures with defined biological activity. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to introduce the (2R)-2,3-dihydro-1H-indol-2-yl moiety into target molecules.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel chiral ligands or organocatalysts used in enantioselective transformations.
• Agrochemical Research: Employed in the discovery and development of new generation pesticides and herbicides with specific modes of action.
• Material Science: Investigated as a monomer or functional unit for creating advanced polymers with unique optical or electronic properties.
• Academic & Contract Research: Used in university and CRO laboratories for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Phenol, 5-Bromo-2-[(2R)-5-Bromo-2,3-Dihydro-1H-Indol-2-Yl]-
CAS No.	1585969-17-0
Molecular Formula	C14H11Br2NO
Molecular Weight	369.05 g/mol
Synonyms	5-Bromo-2-[(2R)-5-bromo-2,3-dihydro-1H-indol-2-yl]phenol; (2R)-2-(5-Bromo-2-hydroxyphenyl)-5-bromo-2,3-dihydro-1H-indole; (R)-2-(5-Bromo-2-hydroxyphenyl)-5-bromoindoline; SCHEMBL23883031; ACH-00002945; BRN 28246995
EINECS	Contact for details

Quality Control

Every batch of Phenol, 5-Bromo-2-[(2R)-5-Bromo-2,3-Dihydro-1H-Indol-2-Yl]- is produced and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity, meeting the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) with full characterization data are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.