Description

[1,1'-Biphenyl]-4-Ethanol, α-(Chloromethyl)-, (αs)- is a chiral, functionalized biphenyl derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. Industries that require high-purity chiral intermediates for the development of active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals will find this product essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and development of advanced, high-performance pesticides and herbicides with specific stereochemical requirements.
• Liquid Crystal Materials: Serves as a precursor for mesogenic compounds used in display technologies due to the rigid biphenyl core.
• Asymmetric Catalysis Ligand Precursor: The structure can be modified to create chiral ligands for transition metal catalysis.
• Material Science Research: Employed in the development of organic semiconductors and advanced polymers.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry and process development.

Basic Information

Item	Detail
Product Name	[1,1'-Biphenyl]-4-Ethanol, α-(Chloromethyl)-, (αs)-
CAS No.	1573000-28-8
Molecular Formula	C15H15ClO
Molecular Weight	246.73 g/mol
Synonyms	(αS)-α-(Chloromethyl)-[1,1'-biphenyl]-4-ethanol; (S)-1-(4-Phenylphenyl)-3-chloro-2-propanol; 4-Biphenylethanol, α-(chloromethyl)-, (αS)-; Chiral biphenyl chloromethyl ethanol; (S)-Biphenyl-4-yl-3-chloro-2-propanol; Biphenyl-based chiral chlorohydrin; (S)-1-([1,1'-Biphenyl]-4-yl)-3-chloropropan-2-ol
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-4-Ethanol, α-(Chloromethyl)-, (αs)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.