Description

5-Bromo-2-Iodo-1H-Indole is a halogenated indole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and high-value building block for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, conductive polymers, and advanced organic frameworks.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays and for studying protein-ligand interactions.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings due to its reactive halogen atoms.
• Academic & Contract Research: Essential for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	5-Bromo-2-Iodo-1H-Indole
CAS No.	1572177-90-2
Molecular Formula	C8H5BrIN
Molecular Weight	321.94 g/mol
Synonyms	5-Bromo-2-iodoindole; 2-Iodo-5-bromo-1H-indole; 1H-Indole, 5-bromo-2-iodo-; 5-Bromo-2-iodo-1H-indole; 1572177-90-2
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodo-1H-Indole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in DMF, DMSO; slightly soluble in organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.