Description

6-Bromo-2-Iodo-1H-Indole is a halogenated indole derivative, a versatile and high-value building block in advanced organic synthesis. Its core value lies in its dual halogen functionality, which enables selective cross-coupling reactions and facilitates the construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, OLED materials, and other functional organic compounds.
• Cross-Coupling Reactions: The bromo and iodo substituents are excellent handles for Suzuki, Stille, and Sonogashira couplings to create complex molecular architectures.
• Chemical Biology: Utilized as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and discovery chemistry in R&D laboratories.

Basic Information

Product Name	6-Bromo-2-Iodo-1H-Indole
CAS No.	1572177-89-9
Molecular Formula	C8H5BrIN
Molecular Weight	321.94 g/mol
Synonyms	6-Bromo-2-iodoindole; 2-Iodo-6-bromo-1H-indole; 1H-Indole, 6-bromo-2-iodo-; 6-Bromo-2-iodo-1H-indole; 6-Br-2-I-indole
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Iodo-1H-Indole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC-MS, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.