Description

(S)-2-Bromo-1-(3-Chloro-4-Fluorophenyl)Ethanol is a high-purity chiral building block of significant importance in modern synthetic chemistry. Its value lies in its defined stereochemistry and functional groups, which make it a critical intermediate for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the (S)-enantiomer can provide specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new reaction pathways involving halogenated and fluorinated aromatics.
• Material Science Precursor: Potential use in synthesizing specialized monomers for advanced polymeric materials with specific optical or electronic properties.

Basic Information

Item	Details
Product Name	(S)-2-Bromo-1-(3-Chloro-4-Fluorophenyl)Ethanol
CAS No.	1568253-17-7
Molecular Formula	C8H7BrClFO
Molecular Weight	263.50 g/mol
Synonyms	(S)-2-Bromo-1-(3-chloro-4-fluorophenyl)ethan-1-ol; (S)-2-Bromo-1-(3-chloro-4-fluorophenyl)ethanol; (S)-1-(3-Chloro-4-fluorophenyl)-2-bromoethanol; (S)-α-Bromo-3-chloro-4-fluorobenzyl alcohol; 1568253-17-7; (S)-enantiomer of 2-Bromo-1-(3-chloro-4-fluorophenyl)ethanol
EINECS	Contact for details

Quality Control

Our (S)-2-Bromo-1-(3-Chloro-4-Fluorophenyl)Ethanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC to confirm enantiomeric excess (ee) and identity verification. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.