Description

(1R)-1-[4-(Trifluoromethoxy)Phenyl]Ethan-1-Ol is a high-purity chiral alcohol building block of significant importance in advanced organic synthesis. Its core value lies in its defined stereochemistry and the presence of the trifluoromethoxy group, which are critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty chemicals and advanced materials with specific optical or electronic properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(1R)-1-[4-(Trifluoromethoxy)Phenyl]Ethan-1-Ol
CAS No.	1567738-33-3
Molecular Formula	C9H9F3O2
Molecular Weight	206.16 g/mol
Synonyms	(R)-1-[4-(Trifluoromethoxy)phenyl]ethanol; (1R)-1-[4-(Trifluoromethoxy)phenyl]ethan-1-ol; (R)-α-Methyl-4-(trifluoromethoxy)benzenemethanol; (R)-1-(4-Trifluoromethoxyphenyl)ethanol; p-(Trifluoromethoxy)phenethyl alcohol, (R)-; (R)-TFMPE; (R)-TMPE; (R)-4-(Trifluoromethoxy)phenethyl alcohol
EINECS	Contact for details

Quality Control

Every batch of (1R)-1-[4-(Trifluoromethoxy)Phenyl]Ethan-1-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.