Description

2-Cyano-3-(Thiazol-5-Yl)Acrylic Acid is a specialized heterocyclic acrylate derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which combines a reactive cyanoacrylate moiety with a thiazole heterocycle, enabling the construction of complex pharmacophores and functional materials. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new generation herbicides and fungicides that leverage the thiazole ring's bioactivity.
• Organic Electronic Materials: Serves as a precursor for electron-accepting units in the design of organic semiconductors and non-fullerene acceptors for solar cells.
• Ligand and Chelator Development: The carboxylic acid and nitrogen-rich structure makes it useful for creating complexing agents in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Synthesis: Employed as a core component in the design of thiazole-based fluorescent dyes and sensors for biological imaging.
• Polymer Modification: Acts as a functional monomer for introducing polar, heterocyclic groups into polymer backbones to alter material properties.

Basic Information

Product Name	2-Cyano-3-(Thiazol-5-Yl)Acrylic Acid
CAS No.	1567641-47-7
Molecular Formula	C7H4N2O2S
Molecular Weight	180.18 g/mol
Synonyms	2-Cyano-3-(1,3-thiazol-5-yl)acrylic acid; 2-Cyano-3-(thiazol-5-yl)prop-2-enoic acid; 3-(Thiazol-5-yl)-2-cyanoacrylic acid; 5-(2-Cyano-2-carboxyvinyl)thiazole; (2Z)-2-Cyano-3-(1,3-thiazol-5-yl)prop-2-enoic acid; Thiazole-5-acrylic acid, 2-cyano-; 1567641-47-7
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-(Thiazol-5-Yl)Acrylic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.