Description

5-Bromo-7-Iodo-2,3-Dihydrobenzofuran is a halogenated dihydrobenzofuran derivative, a versatile and high-value synthetic building block. This compound is critical for advanced organic synthesis, particularly in constructing complex molecular architectures for pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the biological activity of halogenated benzofuran structures.
• Material Science: Acts as a monomer or functionalizing agent in the creation of organic electronic materials, such as OLEDs or semiconductors, due to its electron-rich and modifiable structure.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig).
• Ligand Synthesis: Can be used to synthesize novel chelating ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromo-7-Iodo-2,3-Dihydrobenzofuran
CAS No.	1566912-44-4
Molecular Formula	C8H6BrIO
Molecular Weight	338.94 g/mol
Synonyms	2,3-Dihydro-5-bromo-7-iodobenzofuran; 7-Iodo-5-bromo-2,3-dihydrobenzofuran; 5-Bromo-7-iodo-2,3-dihydro-1-benzofuran; Benzofuran, 5-bromo-7-iodo-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-7-Iodo-2,3-Dihydrobenzofuran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC-MS)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.