Description

(1S)-1-[3-(4-Chlorophenyl)-1,2-Oxazol-5-Yl]Ethan-1-Ol CAS NO 1565845-63-7 is a high-purity chiral intermediate featuring a 1,2-oxazole (isoxazole) core substituted with a chlorophenyl group and a chiral ethanol side chain. This compound is of significant value in pharmaceutical research and development, particularly for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel compounds with potential therapeutic or pesticidal activity.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Serves as a key precursor in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the isoxazole and chlorophenyl motifs.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing for producing complex, high-value specialty chemicals for various industrial applications.
• Academic & R&D: Employed in university and institutional research for studying chiral synthesis methodologies, heterocyclic chemistry, and structure-activity relationships (SAR).
• Ligand & Catalyst Development: Potential use in the preparation of chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	(1S)-1-[3-(4-Chlorophenyl)-1,2-Oxazol-5-Yl]Ethan-1-Ol
CAS No.	1565845-63-7
Molecular Formula	C11H10ClNO2
Molecular Weight	223.66 g/mol
Synonyms	(S)-1-(3-(4-Chlorophenyl)isoxazol-5-yl)ethanol; (1S)-1-[3-(4-Chlorophenyl)-1,2-oxazol-5-yl]ethanol; 5-[(1S)-1-Hydroxyethyl]-3-(4-chlorophenyl)-1,2-oxazole; (S)-5-(1-Hydroxyethyl)-3-(4-chlorophenyl)isoxazole; (S)-3-(4-Chlorophenyl)-5-(1-hydroxyethyl)isoxazole; Chiral Isoxazole Ethanol Derivative; 1565845-63-7
EINECS	Contact for details

Quality Control

Our (1S)-1-[3-(4-Chlorophenyl)-1,2-Oxazol-5-Yl]Ethan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and production. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ISO guidelines where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.