Description

6-Aza-Bicyclo[3.2.1]Octane-2,7-Dione is a high-purity, advanced pharmaceutical intermediate and versatile bicyclic lactam building block. This compound is of significant value for its rigid, three-dimensional scaffold, which is crucial for modulating the pharmacokinetic and pharmacodynamic properties of novel drug candidates. It is primarily sought after by research and development teams in the pharmaceutical and biotechnology sectors for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to introduce conformational constraint and improve metabolic stability.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors of various proteolytic enzymes.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Asymmetric Synthesis: Acts as a chiral precursor or template in stereoselective synthesis.
• Polymer Science: Potential monomer for creating novel polyamides with specific thermal and mechanical properties.

Basic Information

Product Name	6-Aza-Bicyclo[3.2.1]Octane-2,7-Dione
CAS No.	1552322-78-7
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	6-Azabicyclo[3.2.1]octane-2,7-dione; 2,7-Dioxo-6-azabicyclo[3.2.1]octane; 6-Aza-2,7-bicyclooctanedione; Bicyclo[3.2.1]octane-2,7-dione, 6-aza-; (1R,5S)-6-Azabicyclo[3.2.1]octane-2,7-dione (for specific enantiomer); 6-Azabicyclo[3.2.1]octane-2,7-dione, 6-Aza-BCO dione
EINECS	Contact for details

Quality Control

Our 6-Aza-Bicyclo[3.2.1]Octane-2,7-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.