Description

1H-Indazol-3-Amine, 4-Bromo-7-[3-(1-Pyrrolidinyl)Propoxy]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting specific biological pathways. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for oncology and inflammatory diseases.
• Kinase Inhibitor Research: Serves as a core scaffold in the design and development of potent and selective kinase inhibitors due to its indazole pharmacophore.
• Medicinal Chemistry Exploration: Used in structure-activity relationship (SAR) studies to optimize the potency, selectivity, and pharmacokinetic properties of lead compounds.
• Biochemical Probe Development: Employed in the creation of chemical probes for studying specific enzyme functions and cellular signaling pathways in academic and industrial research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and niche APIs.

Basic Information

Product Name	1H-Indazol-3-Amine, 4-Bromo-7-[3-(1-Pyrrolidinyl)Propoxy]-
CAS No.	1548941-53-2
Molecular Formula	C14H19BrN4O
Molecular Weight	339.23 g/mol
Synonyms	4-Bromo-7-[3-(pyrrolidin-1-yl)propoxy]-1H-indazol-3-amine; 4-Bromo-7-(3-pyrrolidin-1-ylpropoxy)-1H-indazol-3-amine; 1548941-53-2; UNII-9J6G89120V; 9J6G89120V; 4-Bromo-7-(3-(pyrrolidin-1-yl)propoxy)-1H-indazol-3-amine; 4-Bromo-7-[3-(1-pyrrolidinyl)propoxy]-1H-indazol-3-amine
EINECS	Contact for details

Quality Control

Our production of 1H-Indazol-3-Amine, 4-Bromo-7-[3-(1-Pyrrolidinyl)Propoxy]- adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines for non-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.