Description

Methyl 3-Chloroisoquinoline-7-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials, offering a versatile scaffold for further chemical modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chlorinated isoquinoline core.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for catalysts, and specialty polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploring new chemical spaces in medicinal chemistry.
• Custom Synthesis: A starting point for the contract manufacturing of complex, customer-specific molecules for various industrial applications.

Basic Information

Product Name	Methyl 3-Chloroisoquinoline-7-Carboxylate
CAS No.	1544665-58-8
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	7-Carbomethoxy-3-chloroisoquinoline; Methyl 3-chloro-7-isoquinolinecarboxylate; 3-Chloro-7-isoquinolinecarboxylic acid methyl ester; 3-Chloroisoquinoline-7-carboxylic acid methyl ester; 1544665-58-8; Methyl 3-chloro-7-quinolinecarboxylate (related); 3-Chloro-7-methoxycarbonylisoquinoline
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloroisoquinoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.