Description

4-Amino-Bicyclo[2.2.2]Octane-1-Propanoic Acid Methyl Ester is a high-purity, functionalized bicyclic building block of significant interest in advanced organic synthesis. Its unique, rigid 3D structure and bifunctional nature make it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained geometry and amino/ester functionalities.
• Agrochemical Synthesis: Acts as a precursor for developing new crop protection agents with potentially enhanced biological activity and environmental profile.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	4-Amino-Bicyclo[2.2.2]Octane-1-Propanoic Acid Methyl Ester
CAS No.	1544665-46-4
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	Methyl 3-(4-Aminobicyclo[2.2.2]octan-1-yl)propanoate; 4-Aminobicyclo[2.2.2]octane-1-propanoic Acid Methyl Ester; 1-(2-Methoxy-2-oxoethyl)-4-aminobicyclo[2.2.2]octane; 4-Amino-1-(2-methoxy-2-oxoethyl)bicyclo[2.2.2]octane; Bicyclo[2.2.2]octane-1-propanoic acid, 4-amino-, methyl ester
EINECS	Contact for details

Quality Control

Our 4-Amino-Bicyclo[2.2.2]Octane-1-Propanoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.