Description

Gestodene-2,2,4,6,6,10-D6 is a deuterium-labeled analog of the progestin gestodene, specifically designed for use as an internal standard in quantitative bioanalytical methods. This high-purity stable isotope-labeled compound is essential for ensuring accuracy and precision in mass spectrometry-based analyses, such as LC-MS/MS, by correcting for matrix effects and instrument variability. It is a critical material for pharmaceutical R&D, clinical research, and forensic toxicology laboratories focused on hormone metabolism, pharmacokinetic studies, and drug monitoring.

Application

• Internal Standard for LC-MS/MS Analysis: Primary use as a quantitative reference standard in bioanalytical method development and validation for gestodene.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug metabolism and exposure.
• Clinical Toxicology and Therapeutic Drug Monitoring (TDM): Enables precise measurement of gestodene levels in biological matrices (plasma, serum, urine) for patient management.
• Metabolite Identification and Profiling: Aids in the identification and quantification of gestodene metabolites in complex biological samples.
• Forensic Analysis: Supports accurate quantification in forensic investigations involving hormonal compounds.
• Quality Control in Reference Material Production: Serves as a calibrant in the production and certification of certified reference materials (CRMs).

Basic Information

Product Name	Gestodene-2,2,4,6,6,10-D6
CAS No.	1542211-40-4
Molecular Formula	C21H20D6O2
Molecular Weight	316.48 g/mol
Synonyms	Gestodene-d6; 13-Ethyl-17-hydroxy-18,19-dinor-17α-pregna-4,15-dien-20-yn-3-one-2,2,4,6,6,10-d6; 17α-Hydroxy-13-ethyl-18,19-dinor-17α-pregna-4,15-dien-20-yn-3-one-d6; Deuterated Gestodene; Gestodene (hexadeuterated); Gestodene Internal Standard; [2,2,4,6,6,10-2H6]-Gestodene
EINECS	Contact for details

Quality Control

Every batch of Gestodene-2,2,4,6,6,10-D6 is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to support its use in regulated environments. Certificates of Analysis (COA) are supplied with each shipment, detailing critical parameters such as chemical purity, isotopic purity (enrichment), and solvent content. Our quality commitment ensures consistency and reliability for your most sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.