Description

Methyl 3-Azabicyclo[3.1.0]Hexane-1-Carboxylate Hcl is a high-purity, pharmaceutically relevant building block featuring a rigid, strained bicyclic scaffold. This compound is valued for its role as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers for constructing complex molecular architectures with enhanced biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained 3D geometry.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and advanced intermediates.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Methyl 3-Azabicyclo[3.1.0]Hexane-1-Carboxylate Hydrochloride
CAS No.	1536392-01-4
Molecular Formula	C8H13NO2 • HCl
Molecular Weight	191.65 g/mol (Free base: 155.19 g/mol)
Synonyms	Methyl 3-azabicyclo[3.1.0]hexane-1-carboxylate hydrochloride; 1-Carbomethoxy-3-azabicyclo[3.1.0]hexane hydrochloride; 3-Azabicyclo[3.1.0]hexane-1-carboxylic acid, methyl ester, hydrochloride; Methyl 1-azabicyclo[3.1.0]hexane-3-carboxylate hydrochloride (isomer); Bicyclo[3.1.0]hexane-1-carboxylic acid, 3-aza-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 3-Azabicyclo[3.1.0]Hexane-1-Carboxylate Hcl is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring material traceability and reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.