Description

(E)-3-(Hydroxy(Phenyl)Methylene)-6-Iodoindolin-2-One is a high-purity synthetic organic compound featuring a unique indolinone scaffold functionalized with iodine and a hydroxy(phenyl)methylene group. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of novel therapeutic agents and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and the generation of compound libraries for high-throughput screening.
• Organic Synthesis Building Block: The iodine moiety provides a handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling the construction of more complex molecular architectures.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in research and production settings.
• Biochemical Probe Development: Potential use in the design and synthesis of molecular probes for studying biological processes and disease mechanisms.

Basic Information

Product Name	(E)-3-(Hydroxy(Phenyl)Methylene)-6-Iodoindolin-2-One
CAS No.	1535204-23-9
Molecular Formula	C15H10INO2
Molecular Weight	363.15 g/mol
Synonyms	6-Iodo-3-[(E)-hydroxy(phenyl)methylene]indolin-2-one; (E)-6-Iodo-3-(hydroxy(phenyl)methylene)indolin-2-one; 3-[(1E)-Hydroxy(phenyl)methylene]-6-iodo-1,3-dihydro-2H-indol-2-one; 6-Iodo-3-[(1E)-hydroxy(phenyl)methylidene]-1,3-dihydro-2H-indol-2-one; (E)-3-(Hydroxybenzylidene)-6-iodoindolin-2-one; 1535204-23-9
EINECS	Contact for details

Quality Control

Our (E)-3-(Hydroxy(Phenyl)Methylene)-6-Iodoindolin-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the stringent requirements for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.