Description

4-Oxo-3,4-Dihydrothieno[3,2-D]Pyrimidine-7-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other therapeutic areas. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other small molecule drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its versatile thienopyrimidine scaffold.
• Chemical Biology: Employed in the development of chemical probes for target identification and validation in biological pathways.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and route development for Active Pharmaceutical Ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for exploring novel heterocyclic chemistry and reaction methodologies.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	4-Oxo-3,4-Dihydrothieno[3,2-D]Pyrimidine-7-Carboxylic Acid
CAS No.	1527518-33-7
Molecular Formula	C7H4N2O3S
Molecular Weight	196.18 g/mol
Synonyms	Thieno[3,2-d]pyrimidine-7-carboxylic acid, 3,4-dihydro-4-oxo-; 4-Oxothieno[3,2-d]pyrimidine-7-carboxylic acid; 4-Hydroxythieno[3,2-d]pyrimidine-7-carboxylic acid; 7-Carboxy-4-hydroxythieno[3,2-d]pyrimidine; 1527518-33-7; Thienopyrimidine-7-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 4-Oxo-3,4-Dihydrothieno[3,2-D]Pyrimidine-7-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.