Description

3-Azabicyclo[3.2.1]Octan-8-Ol Hcl is a high-purity bicyclic amine hydrochloride salt, serving as a sophisticated pharmaceutical intermediate and a versatile building block in organic synthesis. Its rigid, nitrogen-containing scaffold is crucial for constructing complex molecules with specific three-dimensional geometries, enabling the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to create new compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of central nervous system (CNS) active drugs, receptor modulators, and other therapeutic agents.
• Organic Synthesis Building Block: Used in the construction of complex natural product analogs and novel chemical entities due to its constrained bicyclic structure.
• Agrochemical Research: Employed in the development of new pesticides and herbicides where specific stereochemistry influences biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	3-Azabicyclo[3.2.1]Octan-8-Ol Hcl
CAS No.	1523618-33-8
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	8-Hydroxy-3-azabicyclo[3.2.1]octane hydrochloride; 3-Azabicyclo[3.2.1]octan-8-ol hydrochloride; endo-8-Hydroxy-3-azabicyclo[3.2.1]octane HCl; Tropan-3-ol, hydrochloride (8-substituted); 8-Hydroxy-3-azanorbornane hydrochloride; Bicyclo[3.2.1]octan-8-ol, 3-aza-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Azabicyclo[3.2.1]Octan-8-Ol Hcl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for pharmaceutical R&D and advanced synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.