Description

2-Chloro-4H,5H,6H-Cyclopenta[B]Thiophen-4-Amine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Development: Used in the creation of novel herbicides, fungicides, or insecticides, leveraging its fused thiophene-cyclopentane core for unique biological activity.
• Material Science Research: Acts as a precursor for organic electronic materials, such as organic semiconductors or conductive polymers, due to the electron-rich thiophene moiety.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for transition metal catalysis or as a scaffold for organocatalysts.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function or cellular pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical handle.

Basic Information

Product Name	2-Chloro-4H,5H,6H-Cyclopenta[B]Thiophen-4-Amine
CAS No.	1518717-54-8
Molecular Formula	C7H8ClNS
Molecular Weight	173.66 g/mol
Synonyms	2-Chloro-4-amino-4H,5H,6H-cyclopenta[b]thiophene; 4-Amino-2-chloro-4H,5H,6H-cyclopenta[b]thiophene; 2-Chlorocyclopenta[b]thiophen-4-amine; 4H,5H,6H-Cyclopenta[b]thiophen-4-amine, 2-chloro-; 1518717-54-8; 2-Chloro-4H-cyclopenta[b]thiophen-4-amine; 2-Chloro-4,5,6,7-tetrahydrocyclopenta[b]thiophen-4-amine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4H,5H,6H-Cyclopenta[B]Thiophen-4-Amine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and MS. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.