Description

8-Methoxyisoquinoline-5-Carboxylic Acid is a high-purity, functionalized isoquinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the construction of complex heterocyclic systems with potential biological activity. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, agrochemical research, and the synthesis of novel fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients with herbicidal or pesticidal properties.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The isoquinoline core can be modified to create dyes and probes for biochemical sensing and imaging.
• Academic & Industrial R&D: Used in fundamental organic chemistry research to explore new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	8-Methoxyisoquinoline-5-Carboxylic Acid
CAS No.	1516652-25-7
Molecular Formula	C11H9NO3
Molecular Weight	203.19 g/mol
Synonyms	5-Carboxy-8-methoxyisoquinoline; 8-Methoxy-5-isoquinolinecarboxylic Acid; 8-Methoxyisoquinoline-5-carboxylic acid; 1516652-25-7; 8-Methoxy-5-carboxyisoquinoline; 5-Isoquinolinecarboxylic acid, 8-methoxy-; 8-Methoxy-5-isoquinoline carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Methoxyisoquinoline-5-Carboxylic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.