Description

5-Bromo-2-(Cyanomethyl)-6-Fluorobenzimidazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzimidazole core. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzimidazole-based drug candidates, particularly for oncology and antiviral applications.
• Agrochemical Research: Used in the development of new fungicides and herbicides, leveraging its halogenated heterocyclic structure.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for further functionalization in medicinal chemistry and material science research.
• Protease Inhibitor Development: Potential use in creating inhibitors for various enzymatic targets due to the benzimidazole pharmacophore.
• Ligand for Catalysis: Can be utilized to synthesize complex ligands for transition metal catalysis in fine chemical production.

Basic Information

Product Name	5-Bromo-2-(Cyanomethyl)-6-Fluorobenzimidazole
CAS No.	1514433-81-8
Molecular Formula	C9H5BrFN3
Molecular Weight	254.06 g/mol
Synonyms	6-Fluoro-5-bromo-1H-benzimidazole-2-acetonitrile; 2-(Cyanomethyl)-5-bromo-6-fluorobenzimidazole; 5-Bromo-6-fluoro-1H-benzimidazole-2-acetonitrile; 1H-Benzimidazole-2-acetonitrile, 5-bromo-6-fluoro-; 1514433-81-8
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Cyanomethyl)-6-Fluorobenzimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.