Description

Methyl 4-Bromoisoquinoline-1-Carboxylate is a high-value brominated isoquinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its versatile reactivity, particularly in cross-coupling reactions and as a building block for complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the creation of organic semiconductors, ligands for catalysis, and advanced polymers.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form complex biaryl structures.
• Chemical Synthesis: Versatile intermediate for further functionalization, enabling the exploration of new chemical space in medicinal chemistry.

Basic Information

Product Name	Methyl 4-Bromoisoquinoline-1-Carboxylate
CAS No.	1512077-05-2
Molecular Formula	C11H8BrNO2
Molecular Weight	266.09 g/mol
Synonyms	1-Isoquinolinecarboxylic acid, 4-bromo-, methyl ester; Methyl 4-bromo-1-isoquinolinecarboxylate; 4-Bromo-1-isoquinolinecarboxylic acid methyl ester; 4-Bromoisoquinoline-1-carboxylic acid methyl ester; Methyl 4-bromoisoquinoline-1-carboxylate; 1512077-05-2
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromoisoquinoline-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.