Description

Isoquinoline, 1-Chloro-4-Fluoro-6-Nitro- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for developing novel pharmaceutical intermediates and agrochemicals. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and oncological pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the nitro- and fluoro-substituted isoquinoline scaffold.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Investigated for the synthesis of organic semiconductors, fluorescent dyes, and other functional materials due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.

Basic Information

Product Name	Isoquinoline, 1-Chloro-4-Fluoro-6-Nitro-
CAS No.	1508295-23-5
Molecular Formula	C9H4ClFN2O2
Molecular Weight	226.59 g/mol
Synonyms	1-Chloro-4-fluoro-6-nitroisoquinoline; 6-Nitro-1-chloro-4-fluoroisoquinoline; 1-Chloro-4-fluoro-6-nitro-isoquinoline; 1508295-23-5; 1-Chloro-4-fluoro-6-nitroisoquinoline; 4-Fluoro-1-chloro-6-nitroisoquinoline; 6-Nitro-4-fluoro-1-chloroisoquinoline; 1-Chloro-4-fluoro-6-nitro-isoquinoline
EINECS	Contact for details

Quality Control

Our Isoquinoline, 1-Chloro-4-Fluoro-6-Nitro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.