Description

3-Chloro-2-Iodothiophene is a halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing novel thiophene-based scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the thiophene moiety imparts specific biological activity.
• Material Science Precursor: Serves as a monomer or starting material for the creation of conjugated polymers and organic electronic materials, such as organic semiconductors and OLED components.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings, enabling the formation of complex biaryl structures.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis or as a core structure in metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	3-Chloro-2-Iodothiophene
CAS No.	1502188-53-5
Molecular Formula	C4H2ClIS
Molecular Weight	244.48 g/mol
Synonyms	2-Iodo-3-chlorothiophene; 3-Chloro-2-iodothiophene; Thiophene, 3-chloro-2-iodo-; 3-Chloro-2-iodo-thiophene; 3-Chloro-2-iodanylthiophene
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Iodothiophene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.