Description

6,8-Difluoroisoquinoline is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures. The compound is supplied with a high level of purity and batch-to-batch consistency to support critical R&D and scale-up activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the difluoroisoquinoline scaffold imparts desirable properties.
• Material Science: Serves as a building block for creating novel organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Probe Development: Employed in the design and synthesis of fluorescent probes or molecular tags for biological imaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and fluorination reactions.
• Custom Synthesis: Used by fine chemical manufacturers for the bespoke production of complex molecules for client-specific projects.

Basic Information

Product Name	6,8-Difluoroisoquinoline
CAS No.	1499818-92-6
Molecular Formula	C9H5F2N
Molecular Weight	165.14 g/mol
Synonyms	6,8-Difluoro-isoquinoline; Isoquinoline, 6,8-difluoro-; 6,8-Difluoro-2-azanaphthalene; 6,8-Difluoroisoquinoline; 1499818-92-6; 6,8-Difluoro-isoquinoline; 6,8-Difluoro-1-azanaphthalene (tautomeric form).
EINECS	Contact for details

Quality Control

Our 6,8-Difluoroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality assurance ensures material integrity for your most sensitive research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.