Description

2-Thiophenecarboxylic Acid, 5-Amino-, 1,1-Dimethylethyl Ester is a high-purity, specialty organic building block featuring a protected amino-thiophene carboxylic acid scaffold. This compound is critical for researchers and manufacturers requiring precise molecular architecture in advanced synthesis. It is primarily utilized in pharmaceutical research and fine chemical synthesis for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the thiophene moiety can impart specific biological activity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of conductive polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Ligand and Catalyst Development: Useful for creating specialized ligands for metal catalysis or as a component in organocatalysts.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 5-Amino-, 1,1-Dimethylethyl Ester
CAS No.	1498311-57-1
Molecular Formula	C10H15NO2S
Molecular Weight	213.30 g/mol
Synonyms	tert-Butyl 5-amino-2-thiophenecarboxylate; 5-Amino-2-thiophenecarboxylic acid tert-butyl ester; 1,1-Dimethylethyl 5-amino-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-amino-, 1,1-dimethylethyl ester; tert-Butyl 5-aminothiophene-2-carboxylate; 5-Aminothiophene-2-carboxylic acid tert-butyl ester; TBATC; 5-Amino-2-thiophenecarboxylic acid t-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylic Acid, 5-Amino-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.