Description

4-(4-Iodo-1H-Pyrazol-1-Yl)Benzonitrile is a high-purity, heterocyclic organic compound featuring a pyrazole core functionalized with an iodine atom and a benzonitrile group. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to synthesize novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and other targeted therapy research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and library synthesis due to its reactive iodine and nitrile functional groups.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides.
• Material Science: Can be incorporated into the design of organic electronic materials, ligands for catalysis, or metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The aryl iodide moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Potential use in developing molecular probes for studying biological processes and target identification.

Basic Information

Product Name	4-(4-Iodo-1H-Pyrazol-1-Yl)Benzonitrile
CAS No.	1498158-04-5
Molecular Formula	C10H6IN3
Molecular Weight	295.08 g/mol
Synonyms	4-(4-Iodo-1H-pyrazol-1-yl)benzonitrile; 1-(4-Cyanophenyl)-4-iodo-1H-pyrazole; 4-(4-Iodo-pyrazol-1-yl)-benzonitrile; Benzonitrile, 4-(4-iodo-1H-pyrazol-1-yl)-; 4-(4-Iodopyrazol-1-yl)benzonitrile; 4-(4-Iodo-1H-pyrazol-1-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-(4-Iodo-1H-Pyrazol-1-Yl)Benzonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of pharmaceutical and research customers globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.