Description

7-Fluoro-5-Trifluoromethyl-1H-Indole CAS NO 1493799-75-9 is a high-value, multi-fluorinated indole derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine motifs improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty chemicals, including organic semiconductors, liquid crystals, and functional polymers.
• Fluorine Chemistry: An essential substrate for further fluorination reactions and the study of structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	7-Fluoro-5-Trifluoromethyl-1H-Indole
CAS No.	1493799-75-9
Molecular Formula	C9H5F4N
Molecular Weight	203.14 g/mol
Synonyms	1H-Indole, 7-fluoro-5-(trifluoromethyl)-; 5-(Trifluoromethyl)-7-fluoro-1H-indole; 7-Fluoro-5-trifluoromethylindole; 7-Fluoro-5-(trifluoromethyl)indole; 7-Fluoro-α,α,α-trifluoro-5-indolemethane
EINECS	Contact for details

Quality Control

Our 7-Fluoro-5-Trifluoromethyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.