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n-[(11Bs)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl]-1,1,1-Trifluoromethanesulfonamide Triethylamine Adduct CAS NO 1493790-73-0


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CAS No.:1493790-73-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[(11Bs)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl]-1,1,1-Trifluoromethanesulfonamide Triethylamine Adduct is a high-purity, advanced chiral organophosphorus compound primarily used as a sophisticated ligand or catalyst precursor in asymmetric synthesis. This product matters for its role in enabling highly selective chemical transformations, which are critical for developing enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

  • As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and C-H activation.
  • As a key intermediate or catalyst precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
  • In academic and industrial research for developing novel asymmetric synthetic methodologies.
  • For the synthesis of complex natural products and other chiral molecules in fine chemical manufacturing.
  • Potential use in the development of advanced materials and specialty polymers where chiral induction is required.

Basic Information

Product Name n-[(11Bs)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl]-1,1,1-Trifluoromethanesulfonamide Triethylamine Adduct
CAS No. 1493790-73-0
Molecular Formula C27H22F3NO5PS · C6H15N
Molecular Weight Contact for details
Synonyms (11bS)-4-[[(Trifluoromethyl)sulfonyl]amino]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin Triethylamine Adduct; (S)-DTBM-SEGPHOS-Derived Triflamide Triethylamine Adduct; BINAP-Derived Chiral Phosphoramidate Adduct; Triethylamine Adduct of a Chiral Dinaphthodioxaphosphepin Triflamide; Asymmetric Synthesis Ligand Precursor; Chiral Organophosphorus Compound Adduct
EINECS Contact for details

Quality Control

Our n-[(11Bs)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl]-1,1,1-Trifluoromethanesulfonamide Triethylamine Adduct is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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