Description

1-(4-Chlorobenzyl)-5-Methoxy-2-Methylindole-3-Acetic Acid is a high-purity indole acetic acid derivative, a crucial advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel therapeutic agents, offering researchers and manufacturers a reliable building block for complex molecular development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical producers focused on developing new drug candidates, particularly in areas requiring specialized heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies targeting inflammatory pathways and enzyme inhibition.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex indole-based compounds with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up production.
• Academic Research: Utilized in university and institutional laboratories for medicinal chemistry projects and the development of new synthetic methodologies.

Basic Information

Product Name	1-(4-Chlorobenzyl)-5-Methoxy-2-Methylindole-3-Acetic Acid
CAS No.	1469902-72-4
Molecular Formula	C19H18ClNO3
Molecular Weight	343.80 g/mol
Synonyms	5-Methoxy-2-methyl-1-[(4-chlorophenyl)methyl]-1H-indole-3-acetic acid; 1-[(4-Chlorophenyl)methyl]-5-methoxy-2-methyl-1H-indole-3-acetic acid; 1-(4-Chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid; 1H-Indole-3-acetic acid, 1-[(4-chlorophenyl)methyl]-5-methoxy-2-methyl-; UNII-7X9Q9K8Q4F; 7X9Q9K8Q4F; SCHEMBL21821027; DTXSID701330571
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorobenzyl)-5-Methoxy-2-Methylindole-3-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.