Description

Trv-130 Fumarate is a high-purity, non-opioid analgesic compound designed for advanced pharmaceutical research and development. This active pharmaceutical ingredient (API) is critical for developing novel pain management therapies with a potentially improved safety profile. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the discovery and formulation of next-generation analgesic drugs.

Application

• Pharmaceutical R&D: Primary use in the research and development of novel non-opioid analgesic medications.
• Preclinical Studies: Serves as a key reference standard and active ingredient in pharmacological and toxicological testing.
• Analytical Method Development: Used as a standard for developing and validating HPLC, LC-MS, and other analytical methods for quality control.
• Formulation Development: Employed in the creation of various dosage forms, including tablets, capsules, and injectables, during formulation studies.
• Chemical Synthesis: Acts as a crucial intermediate or final product in the synthesis of specialized pharmaceutical compounds.
• Reference Material: Provides a certified standard for quality assurance and regulatory compliance testing in manufacturing.

Basic Information

Product Name	Trv-130 Fumarate
CAS No.	1467617-09-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Oliceridine Fumarate; TRV-130; (3-methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]ethyl})amine fumarate; N-[(3-methoxythiophen-2-yl)methyl]-2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]ethan-1-amine fumarate
EINECS	Contact for details

Quality Control

Our Trv-130 Fumarate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and LC-MS to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) are provided and can be tailored to support regulatory filings for clinical trials or commercial manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.