Description

5-(4-Cyclopropyl-4H-1,2,4-Triazol-3-Yl)Thiophen-3-Amine is a high-purity heterocyclic organic compound featuring a fused triazole-thiophene core structure. This molecule is a critical pharmaceutical intermediate valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the life sciences sector engaged in drug discovery and development programs, particularly those targeting kinase inhibition and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology and anti-infective research.
• Kinase Inhibitor Precursor: Used in the development of small molecule inhibitors targeting specific kinase enzymes involved in cell signaling pathways.
• Agrochemical Research: Serves as a core structure for developing new active ingredients for crop protection products.
• Chemical Biology Probe: Employed in academic and industrial research to study biological processes and protein functions.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers and organic electronic materials.

Basic Information

Item	Detail
Product Name	5-(4-Cyclopropyl-4H-1,2,4-Triazol-3-Yl)Thiophen-3-Amine
CAS No.	1464091-63-1
Molecular Formula	C9H9N5S
Molecular Weight	219.27 g/mol
Synonyms	3-Thiophenamine, 5-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)-; 5-(4-Cyclopropyl-1H-1,2,4-triazol-3-yl)thiophen-3-amine; 5-(4-Cyclopropyl-4H-1,2,4-triazol-3-yl)-3-thiophenamine; 1464091-63-1; 5-(4-Cyclopropyl-1,2,4-triazol-3-yl)thiophen-3-amine; 3-Amino-5-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)thiophene
EINECS	Contact for details

Quality Control

Our 5-(4-Cyclopropyl-4H-1,2,4-Triazol-3-Yl)Thiophen-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.