Description

7-tert-Butyl 2-Ethyl 7-Azabicyclo[2.2.1]Heptane-2,7-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique azabicyclo[2.2.1]heptane scaffold. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, where its structural complexity enables the creation of molecules with specific stereochemistry and biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Utilized in chiral synthesis due to the rigid bicyclic structure, which can impart desired stereochemical outcomes.
• Ligand and Catalyst Development: Potential use in the development of novel ligands for catalysis or as a core structure in chemical biology probes.
• Process Chemistry & Scale-Up: Supports the development and optimization of robust, scalable synthetic routes for API manufacturing under GMP conditions.

Basic Information

Product Name	7-tert-Butyl 2-Ethyl 7-Azabicyclo[2.2.1]Heptane-2,7-Dicarboxylate
CAS No.	1461706-87-5
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	7-Azabicyclo[2.2.1]heptane-2,7-dicarboxylic acid, 2-ethyl 7-(1,1-dimethylethyl) ester; 2-Ethyl 7-tert-butyl 7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate; tert-Butyl 2-ethyl 7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate; 7-(tert-Butoxycarbonyl)-2-(ethoxycarbonyl)-7-azabicyclo[2.2.1]heptane; Bicyclo[2.2.1]heptane-2,7-dicarboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 7-tert-Butyl 2-Ethyl 7-Azabicyclo[2.2.1]Heptane-2,7-Dicarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including those for pre-clinical and early-phase clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.