Description

3-Amino-5-tert-Butyl-2,3-Dihydro-1H-Indol-2-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its value lies in its role as a key precursor for the development of novel bioactive molecules, particularly in medicinal chemistry research. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality raw materials for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides with specific biological activity.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and complex organic molecules.
• Academic & R&D Laboratories: Utilized in universities and research institutions for methodological development and exploratory synthesis.
• Contract Manufacturing (CMO/CDMO): A key raw material for contract organizations producing active pharmaceutical ingredients (APIs) and advanced intermediates under cGMP.

Basic Information

Item	Details
Product Name	3-Amino-5-tert-Butyl-2,3-Dihydro-1H-Indol-2-One Hydrochloride
CAS No.	1461706-05-7
Molecular Formula	C12H17ClN2O
Molecular Weight	240.73 g/mol
Synonyms	5-tert-Butyl-3-aminoindolin-2-one hydrochloride; 3-Amino-5-tert-butylindolin-2-one HCl; 2H-Indol-2-one, 3-amino-1,3-dihydro-5-(1,1-dimethylethyl)-, hydrochloride (1:1); 5-tert-Butyl-3-amino-2-indolinone hydrochloride; 3-Amino-5-(tert-butyl)-2,3-dihydro-1H-indol-2-one hydrochloride; 5-tert-Butyl-3-aminooxindole hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-5-tert-Butyl-2,3-Dihydro-1H-Indol-2-One Hydrochloride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development and commercial projects requiring standards from laboratory to cGMP grade.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.