Description

n-Boc-n-Methylpiperazine-D3 is a deuterated building block of significant importance in pharmaceutical research and development. This compound, with CAS number 1459230-58-0, is specifically designed for use in the synthesis of isotopically labeled drug candidates and metabolites. It is primarily utilized by medicinal chemists and analytical scientists in the pharmaceutical and biotechnology industries for applications in drug discovery, pharmacokinetic studies, and mass spectrometry.

Application

• Deuterated Pharmaceutical Synthesis: A key precursor for incorporating stable deuterium isotopes into active pharmaceutical ingredients (APIs) to create deuterated drugs with potentially improved metabolic profiles.
• Metabolite Identification & Tracing: Used in the synthesis of internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS) to accurately quantify drug metabolites in biological samples.
• Pharmacokinetic (PK) and Absorption, Distribution, Metabolism, and Excretion (ADME) Studies: Enables precise tracking of a drug's fate in the body through the use of isotopically labeled analogs.
• Mechanism of Action (MoA) Research: Serves as a tool compound in biochemical and pharmacological research to investigate drug-receptor interactions and metabolic pathways.
• High-Purity Reference Standard: Can be supplied as a certified reference material for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	n-Boc-n-Methylpiperazine-D3
CAS No.	1459230-58-0
Molecular Formula	C10H17D3N2O2
Molecular Weight	203.30 g/mol
Synonyms	1-Boc-4-Methylpiperazine-d3; tert-Butyl 4-methylpiperazine-1-carboxylate-d3; 1-(tert-Butoxycarbonyl)-4-methylpiperazine-d3; N-Boc-N'-Methylpiperazine-d3; 4-Methyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester-d3; Boc-4-Methylpiperazine-d3; N-Boc-4-Methylpiperazine-d3; N-Methyl-N-Boc-piperazine-d3
EINECS	Contact for details

Quality Control

Our n-Boc-n-Methylpiperazine-D3 is manufactured under strict quality systems to ensure high chemical and isotopic purity suitable for sensitive research applications. Each batch is characterized by advanced analytical techniques including NMR (¹H, ¹³C), HPLC, and Mass Spectrometry to confirm structure, chemical purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.