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Boronic Acid, B-(1,2-Dihydro-1-Methyl-2-Oxo-3-Pyridinyl)- CAS NO 1454558-46-3


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CAS No.:1454558-46-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Boronic Acid, B-(1,2-Dihydro-1-Methyl-2-Oxo-3-Pyridinyl)- is a specialized heterocyclic boronic acid derivative, a key building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates targeting neurological and oncological pathways.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motif can contribute to novel modes of action.
  • Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and sensors.
  • Suzuki-Miyaura Cross-Coupling: The principal application is as a boron-containing coupling partner with aryl or vinyl halides to form new carbon-carbon bonds under palladium catalysis.
  • Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
  • Chemical Biology Probes: Employed in the creation of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name Boronic Acid, B-(1,2-Dihydro-1-Methyl-2-Oxo-3-Pyridinyl)-
CAS No. 1454558-46-3
Molecular Formula C8H10BNO3
Molecular Weight 179.00 g/mol
Synonyms 1-Methyl-2-oxo-1,2-dihydropyridin-3-ylboronic acid; 3-Pyridinylboronic acid, 1,2-dihydro-1-methyl-2-oxo-; (1-Methyl-2-oxo-1,2-dihydropyridin-3-yl)boronic acid; 3-Borono-1-methylpyridin-2(1H)-one; 1-Methyl-2-oxo-1,2-dihydro-3-pyridineboronic acid
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Quality Control

Our Boronic Acid, B-(1,2-Dihydro-1-Methyl-2-Oxo-3-Pyridinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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