Description

5-Bromobenzo[1,3]Dioxole-4-Boronic Acid CAS NO 1451392-88-3 is a high-purity, functionalized boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for compounds containing the benzodioxole scaffold.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic structures.
• Material Science: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, through polymerization or functionalization.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Custom Synthesis: Employed in contract manufacturing and custom synthesis projects to produce tailored, high-value specialty chemicals.

Basic Information

Product Name	5-Bromobenzo[1,3]Dioxole-4-Boronic Acid
CAS No.	1451392-88-3
Molecular Formula	C7H6BBrO4
Molecular Weight	244.84 g/mol
Synonyms	5-Bromo-1,3-benzodioxole-4-boronic acid; (5-Bromo-1,3-benzodioxol-4-yl)boronic acid; 4-Borono-5-bromo-1,3-benzodioxole; 5-Bromo-4-boronobenzodioxole; 5-Bromobenzodioxole-4-boronic Acid Pinacol Ester (common protected form); 5-Br-BDBA; B-1451392-88-3
EINECS	Contact for details

Quality Control

Our 5-Bromobenzo[1,3]Dioxole-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Boronic Acid)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.