Description

2-(Methylthio)Thiophene-4-Boronic Acid is a high-purity organoboronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly for developing novel active ingredients and functional organic molecules.

Application

• Pharmaceutical Intermediate: Key synthon for constructing thiophene-containing drug candidates in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with thiophene backbones.
• Material Science: Building block for creating conjugated polymers and organic semiconductors used in OLEDs, OFETs, and solar cells.
• Chemical Research: A versatile reagent in academic and industrial R&D for palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-(Methylthio)Thiophene-4-Boronic Acid
CAS No.	1451392-40-7
Molecular Formula	C6H7BO2S2
Molecular Weight	186.06 g/mol
Synonyms	4-Borono-2-(methylthio)thiophene; 2-(Methylsulfanyl)thiophene-4-boronic acid; (2-(Methylthio)thiophen-4-yl)boronic acid; 2-Methylthiothiophene-4-boronic Acid; Thiophene-4-boronic acid, 2-(methylthio)-; 1451392-40-7; 2-Methylmercaptothiophene-4-boronic Acid
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)Thiophene-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0% (as boronic acid)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.