Description

3-Chloro-2-Formyl-4-Methylphenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl and a boronic acid group on a chlorinated aromatic ring, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients through cross-coupling reactions like the Suzuki-Miyaura reaction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for small molecule drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and boronic acid functionalities.
• Material Science Research: Employed in the creation of advanced organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Chloro-2-Formyl-4-Methylphenylboronic Acid
CAS No.	1451391-37-9
Molecular Formula	C8H8BClO3
Molecular Weight	198.41 g/mol
Synonyms	(3-Chloro-2-formyl-4-methylphenyl)boronic acid; 2-Formyl-3-chloro-4-methylbenzeneboronic acid; 3-Chloro-2-formyl-p-tolylboronic acid; 4-Methyl-3-chloro-2-formylphenylboronic acid; Boronic acid, B-(3-chloro-2-formyl-4-methylphenyl)-; 1451391-37-9
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Formyl-4-Methylphenylboronic Acid is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.