Description

5-Bromo-3-Methylpyridine-4-Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary importance lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable synthesis of novel compounds for drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Ligand & Catalyst Development: Serves as a building block for creating novel bidentate ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Item	Details
Product Name	5-Bromo-3-Methylpyridine-4-Boronic Acid
CAS No.	1451391-27-7
Molecular Formula	C7H7BBrNO2
Molecular Weight	215.85 g/mol
Synonyms	4-Borono-5-bromo-3-methylpyridine; (5-Bromo-3-methylpyridin-4-yl)boronic acid; 5-Bromo-3-methyl-4-pyridineboronic acid; 3-Methyl-5-bromopyridine-4-boronic acid; 4-Pyridineboronic acid, 5-bromo-3-methyl-; 1451391-27-7; 5-Br-3-Me-4-PyB(OH)2
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Methylpyridine-4-Boronic Acid is produced and tested under a strict quality management system. We guarantee high purity and consistency to meet the rigorous demands of research and commercial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.