share

(Alpha2R,Alpha2’R,1S)-Alpha2-Ethenyl-Alpha2’-Phenyl-[1,1’-Binaphthalene]-2,2’-Dimethanol CAS NO 1451057-21-8


Unit Price:

CAS No.:1451057-21-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(Alpha2R,Alpha2’R,1S)-Alpha2-Ethenyl-Alpha2’-Phenyl-[1,1’-Binaphthalene]-2,2’-Dimethanol is a sophisticated chiral binaphthyl derivative, a high-value intermediate in advanced organic synthesis. Its unique three-dimensional structure makes it a critical component for constructing complex molecular architectures with precise stereochemical control. This compound is essential for research and development in the pharmaceutical and fine chemical sectors, particularly for applications requiring high enantiomeric purity.

Application

  • Chiral Ligand Precursor: Serves as a key building block for synthesizing novel, enantiopure ligands used in asymmetric catalysis.
  • Pharmaceutical Intermediate: Employed in the research and development of active pharmaceutical ingredients (APIs) where specific stereochemistry is crucial for biological activity.
  • Advanced Material Synthesis: Used in the creation of chiral functional materials, including liquid crystals and organic semiconductors.
  • Asymmetric Synthesis Catalyst: Acts as a core structural element for developing organocatalysts or metal-complex catalysts for enantioselective transformations.
  • Analytical Chemistry: Can be utilized as a chiral selector or stationary phase modifier in chromatographic separation techniques.

Basic Information

Product Name (Alpha2R,Alpha2’R,1S)-Alpha2-Ethenyl-Alpha2’-Phenyl-[1,1’-Binaphthalene]-2,2’-Dimethanol
CAS No. 1451057-21-8
Molecular Formula C32H26O2
Molecular Weight 442.55 g/mol
Synonyms (1S)-1,1'-Bi-2-naphthol, 2,2'-Bis(ethenylphenyl)methanol derivative; (R,R,S)-VINBINOL Derivative; 1,1'-Binaphthalene-2,2'-dimethanol, α-ethenyl-α'-phenyl-, (αR,α'R,1S)-; Chiral Binaphthyl Diol Derivative; Atropisomeric Binaphthyl Compound; BINOL-based Chiral Auxiliary; (αR,α'R,1S)-2,2'-Bis(1-phenylvinyl)-[1,1'-binaphthalene]-2,2'-diol (tautomeric form)
EINECS Contact for details

Quality Control

Our (Alpha2R,Alpha2’R,1S)-Alpha2-Ethenyl-Alpha2’-Phenyl-[1,1’-Binaphthalene]-2,2’-Dimethanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (assay), enantiomeric excess (ee), and related substances is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage under inert atmosphere (e.g., argon or nitrogen) is recommended to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

Complete Your RFQ

0/ 2000

Why choose US

Trusted Manufacturer

With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.

Rigorous Quality Assurance

Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

Advanced R&D Expertise

Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.