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(Alpha2R,Alpha2’R,1S)-Alpha2-Ethenyl-Alpha2’-Phenyl-[1,1’-Binaphthalene]-2,2’-Dimethanol CAS NO 1451057-21-8
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CAS No.:1451057-21-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(Alpha2R,Alpha2’R,1S)-Alpha2-Ethenyl-Alpha2’-Phenyl-[1,1’-Binaphthalene]-2,2’-Dimethanol is a sophisticated chiral binaphthyl derivative, a high-value intermediate in advanced organic synthesis. Its unique three-dimensional structure makes it a critical component for constructing complex molecular architectures with precise stereochemical control. This compound is essential for research and development in the pharmaceutical and fine chemical sectors, particularly for applications requiring high enantiomeric purity.
Application
- Chiral Ligand Precursor: Serves as a key building block for synthesizing novel, enantiopure ligands used in asymmetric catalysis.
- Pharmaceutical Intermediate: Employed in the research and development of active pharmaceutical ingredients (APIs) where specific stereochemistry is crucial for biological activity.
- Advanced Material Synthesis: Used in the creation of chiral functional materials, including liquid crystals and organic semiconductors.
- Asymmetric Synthesis Catalyst: Acts as a core structural element for developing organocatalysts or metal-complex catalysts for enantioselective transformations.
- Analytical Chemistry: Can be utilized as a chiral selector or stationary phase modifier in chromatographic separation techniques.
Basic Information
| Product Name | (Alpha2R,Alpha2’R,1S)-Alpha2-Ethenyl-Alpha2’-Phenyl-[1,1’-Binaphthalene]-2,2’-Dimethanol |
| CAS No. | 1451057-21-8 |
| Molecular Formula | C32H26O2 |
| Molecular Weight | 442.55 g/mol |
| Synonyms | (1S)-1,1'-Bi-2-naphthol, 2,2'-Bis(ethenylphenyl)methanol derivative; (R,R,S)-VINBINOL Derivative; 1,1'-Binaphthalene-2,2'-dimethanol, α-ethenyl-α'-phenyl-, (αR,α'R,1S)-; Chiral Binaphthyl Diol Derivative; Atropisomeric Binaphthyl Compound; BINOL-based Chiral Auxiliary; (αR,α'R,1S)-2,2'-Bis(1-phenylvinyl)-[1,1'-binaphthalene]-2,2'-diol (tautomeric form) |
| EINECS | Contact for details |
Quality Control
Our (Alpha2R,Alpha2’R,1S)-Alpha2-Ethenyl-Alpha2’-Phenyl-[1,1’-Binaphthalene]-2,2’-Dimethanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (assay), enantiomeric excess (ee), and related substances is supplied with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage under inert atmosphere (e.g., argon or nitrogen) is recommended to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 97.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Single Impurity (HPLC) | ≤ 0.5% |
| Total Impurities (HPLC) | ≤ 1.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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